An In Vitro study to evaluate growth of candida albicans on three different forms of denture adhesives
An In Vitro study to evaluate growth of candida albicans on three different forms of denture adhesives
Abstract
The purpose of this study is to comprehensively evaluate and analyse the influenceexerted by three distinct forms of denture adhesives on the growth and proliferation of Candida
albicans, a common fungal organism implicated in oral infections.Growth of Candida albicans was tested on Poligrip powder, cream and strip form of adhesives. 160 wax patterns were processed into denture base resin specimensusing heat-cure techniques. Candida albicans suspension was prepared and inoculated onto the specimens. Four groups of specimens were treated with different forms of Poligrip dentureadhesives while one group served as control. Specimens were incubated for various periods,and pH was measured. Colony counting was conducted to assess candidal growth on thespecimens. One-way ANOVA and Tukey’s post hoc test were performed to determine thesignificance among mean values.At both 6 and 24-hour intervals, the strips and powder forms exhibited more
favourable pH levels and fewer colony forming units (CFUs), while at 48 and 120-hour
intervals, the strips form showed the most favourable pH and the lowest number of CFUs.
Specifically, the strips form demonstrated the lowest colony count, followed by the powder
form, then the cream group, indicating that the control group had the highest Candida albicans
growth. study concluded that The strip form of denture adhesive showed least number of colony forming units
and showed better antifungal property as compared to other forms.
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