Role of various artifacts in histopathology : a narrative review

artifacts in histopathology

  • HIMANSHU SINGH YES
  • ANKIT GOYAL Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
  • ARUNEE GARG Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
  • URVASHI TOMAR Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
  • DHEERAJ SHARMA Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
  • BHUVNESH AIREN Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
Keywords: Artifacts, Diagnosis, Histopathology, Tissue sample

Abstract

The noteworthiness of appropriate handling of tissue samples is valuable for histopathological diagnosis. Preciseness of tissue sample diagnosis by pathologists is profoundly reliant on the proficiency of histotechnologists. Artifacts are known as fault or glitches that happens at several stages like collection of sample, during processing, embedding, and mounting of the tissue sample. Thus, it is crucial to determine the frequently occurring artifacts. In this review, literature or information on artifacts is discussed. English language articles were scrutinize in plentiful directory or databases like Pubmed, Scopus, Web of Science, Science Direct, Google Scholar.

Author Biographies

ANKIT GOYAL, Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016

DR.ANKIT GOYAL

MDS

ASSISTANT PROFESSOR

DEPARTMENT OF ORAL & MAXILLOFACIAL PATHOLOGY & ORAL MICROBIOLOGY

INDEX INSTITUTE OF DENTAL SCIENCES, INDORE, MADHYA PRADESH-452016

EMAIL: [email protected]

ARUNEE GARG, Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016
  1. ARUNEE GARG

MDS

ASSISTANT PROFESSOR

DEPARTMENT OF ORAL AND MAXILLOFACIAL PATHOLOGY AND ORAL MICROBIOLOGY

INDEX INSTITUTE OF DENTAL SCIENCES, INDORE, MADHYA PRADESH, INDIA-452016

Email: [email protected]

URVASHI TOMAR, Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016

DR.URVASHI TOMAR

MDS

PROFESSOR

DEPARTMENT OF ORAL & MAXILLOFACIAL PATHOLOGY & ORAL MICROBIOLOGY

INDEX INSTITUTE OF DENTAL SCIENCES, INDORE, MADHYA PRADESH-452016

EMAIL: [email protected]

DHEERAJ SHARMA, Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016

DR.DHEERAJ SHARMA

MDS

PROFESSOR & HEAD

DEPARTMENT OF ORAL & MAXILLOFACIAL PATHOLOGY & ORAL MICROBIOLOGY

INDEX INSTITUTE OF DENTAL SCIENCES, INDORE, MADHYA PRADESH-452016

EMAIL: [email protected]

BHUVNESH AIREN, Index Institute Of Dental Sciences, Indore, Madhya Pradesh,India-452016

DR.BHUVNESH AIREN

MDS

ASSOCIATE PROFESSOR

DEPARTMENT OF PUBLIC HEALTH DENTISTRY

INDEX INSTITUTE OF DENTAL SCIENCES,INDORE,MADHYA PRADESH

EMAIL: [email protected]

References

1. Bindhu p, krishnapillai r, thomas p, jayanthi p. Facts in artifacts. J oral maxillofac pathol 2013;17:397 401
2. Meghana, s. M., & ahmedmujib, b. R. (2007). Surgical artefacts in oral biopsy specimens: punch biopsy compared to conventional scalpel biopsy. Journal of oral and maxillofacial pathology, 11(1), 11.

3. Ficarra g, mcclintock b, hansen ls. Artefacts created during oral biopsy procedures. J craniomaxillofac surg 1987;15:34 7.

4. Margarone je, natiella jr, vaughan cd. Artifacts in oral biopsy specimens. J oral maxillofac surg 1985;43:163 72.
5. Pizzolato p. Formalin pigment (acid hematin) and related pigments. Am j med technol 1976;42:436 40
6. Lovas gl, howell re, peters e, gardner dg. Starch artifacts in oral cytologic specimens. Oral surg oral med oral pathol 1985;60:195 6
7. Bancroft jd, gamble m. Theory and practice of histological technique. 6th ed. Philadelphia: churchill livingstone, elsevier health sciences; 2008. P. 53 105
8. Rastogi v, puri n, arora s, kaur g, yadav l, sharma r, et al. Artefacts: a diagnostic dilemma – a review. J clin diagn res 2013;7:2408 13.
9. Kepes jj, oswald o. Tissue artefacts caused by sponge in embedded cassettes. Am j surg pathol 1991;15:810 2.
10. Farell dj, thompson pj, morley ar. Tissue artefacts caused by sponges. J clin pathol 1992;45:923 4.
11. Culing cf, allison rt, barr wt, culling ca. In microtome and microtomy. Cellular pathology techniques. 4th ed. United kingdom: oxford university press; 1985

12. Faoláin eo, hunter mb, byrne jm, kelehan p, lambkin ha, byrne hj, et al. Raman spectroscopic evaluation of efficacy of current paraffin wax section dewaxing agents. J histochem cytochem 2005;53:121 9
13. Chatterjee s. Artefacts in histopathology. J oral maxillofac pathol 2014;18:s111 6.
14. Rolls go, farmer nj, hall jb. Artefacts in histological and cytological preparations. 1st ed. Melbourne (australia): leica biosystems pty ltd; 2012;106
15. Carleton hm, drury ra, wallington ea. Carleton’s text book of histological techniques. 5th ed. Vol. 41. The university of michigan: oxford university press; 1967. P. 269
16. Krishnanand ps, kamath vv, nagaraja a, badni m. Artefacts in oral mucosal biopsies: a review. J orofac sci 2010;2:57-62
17. Oliver rj, sloan p, pemberton mn. Oral biopsies: methods and applications. Br dent j 2004;196:329 33.
18. Abbey lm, sweeney wt. Fixation artifacts in oral biopsy specimens. Va dent j 1972;49:31 4.
Published
2024-06-27
How to Cite
HIMANSHU SINGH, GOYAL, A., GARG, A., TOMAR, U., SHARMA, D., & AIREN, B. (2024). Role of various artifacts in histopathology : a narrative review. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 10(2). https://doi.org/10.21276//ujds.2024.10.2.19

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