Tooth and Nail Syndrome- A rare case report

  • Sameeksha Bhardwaj K D Dental college and hospital, mathura
Keywords: Keywords: Ectodermal dysplasia, Tooth and Nail Syndrome, Hypodontia


Abstract: A uncommon autosomal dominant condition called Witkop's syndrome is marked by irregularities in the teeth and nails. It is an ectodermal dysplasia variation, which is thought to affect 1 in 100,000 live births. As a result, it is extremely difficult to identify in the general population due to its low prevalence and lack of distinguishing characteristics. The case study's objectives are to add to the body of existing knowledge by providing a useful approach to discovering the uncommon.


1. Arora, V., Agrawal, K. K., Mishra, A., & Chandra, A. (2016). Witkop's syndrome: A case report. Journal of oral biology and craniofacial research, 6(1), 79–81.
2. Bharti, Kusum & Lahori, Manesh & Yadav, Pramod. (2019). WITKOP TOOTH AND NAIL SYNDROME: A CASE REPORT 1 2 3. 10.1136/jmg.33.8.707.PubMed.
3. Hodges SJ, Harley KE. Witkop tooth and nail syndrome: report of two cases in a family. Int J Paediatr Dent. 1999 Sep;9(3):207-11. doi: 10.1046/j.1365-263x.1999.00128.x. PMID: 10815578.
4. Davidson D. The function and evolution of Msx genes: pointers and paradoxes. Trends Genet. 1995 Oct;11(10):405-11. doi: 10.1016/s0168-9525(00)89124-6. PMID: 7482767.
5. Subramaniam, P., and R. Neeraja. "Witkop's tooth and nail syndrome: a multifaceted approach to dental management." Journal of Indian Society of Pedodontics and Preventive Dentistry 26.1 (2008): 22.
6. Cakur, B., et al. "Nonsyndromic oligodontia in permanent dentition: Three siblings." Internet J Dent Sci 3.2 (2006).
How to Cite
Bhardwaj, S. (2023). Tooth and Nail Syndrome- A rare case report. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 9(3).