Unusual Presentation of a Huge Mucoepidermoid Carcinoma – A Case Report
Mucoepidermoid Carcinoma
Keywords:
MEC, Parotid gland, Malignant neoplasm
Abstract
Amongst all the carcinoma, malignant neoplasm of major salivary glands, Mucoepidermoid carcinomas holds the most common malignant neoplasm comprising of approximately 15.5% of all the cases. It most commonly involves the parotid gland. It usually occurs in middle- aged people with slightly female predilection. Mandible is more commonly involved as compared to the maxilla. Treatment modalities mainly depends on the severity and grade of the tumor as well as the adequacy of resection. The purpose of this case report is to emphasize the clinical features, radiographic features, diagnosis and the treatment modalities of Mucoepidermoid carcinoma.
References
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12. Auclair PL, Goode RK, Ellis GL. Mucoepidermoid carcinoma of intraoral salivary glands. Evaluation on and application on of grading criteria in 143 cases. Cancer 1992;69:2021-30.
13. Kullaje S, Prabhu V, Thomas S, Keshava PY. Mucoepidermoid carcinoma of the anterior maxilla: A rare entity. Arch Med Health Sci 2014;2:64-6.
14. F. R. Pires, O. P. Almeida, M. A. Lopes, D. E. C. Perez, and L. P. Kowalski, “Central mucoepidermoid carcinoma of the mandible: report of four cases with long-term follow-up,” International Journal of Oral and Maxillofacial Surgery, vol. 32, no. 4, pp. 378–382, 2003.
15. Raut DL, Khedkar SA. Primary intraosseous mucoepidermoid carcinoma of the maxilla: A case report and review of literature. Dentomaxillofac Radiol 2009;38:163-8.
16. Brookstone MS, Huvos AG. Central salivary tumors of the maxilla and mandible: a clinicapathologic study of 11 cases with an analysis of the literature. J Oral Maxillofac Surg 1992; 50:229–236.
17. Dhawan IK, Bhargava S, Nayak NC, Gupta RK. Central salivary gland tumors of jaws. Cancer 1970; 26: 211–217.
18. DL Raut, SA Khedkar. Primary intraosseous mucoepidermoid carcinoma of the maxilla: a case report and review of literature. Dentomaxillofacial Radiology (2009) 38, 163–168.
19. Alos L, Lujan B, CasƟ llo M, Nadal A, Carreras M, Caballero M, et al. Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands. Am J Surg Pathol 2005;29:806-13.
20. Handra-Luca A, Lamas G, Bertrand JC, Fouret P. MUC1, MUC2, MUC4, and MUC5AC expression in salivary gland mucoepidermoid carcinoma: Diagnostic and prognostic implications. Am J Surg Pathol 2005;29:881-9.
21. Yoon JH, Ahn SG, Kim SG, Kim J. Calcifications in a clear cell mucoepidermoid carcinoma of the hard palate. Int. J Oral Maxillofac. Surg. 2005; 34(8):927-9.
2. Foote FW Jr, Frazell EL. Tumors of the major salivary glands. Cancer 1953;6:1065-133.
3. Cornog JL, Gray SR. Surgical and clinical pathology of salivary gland tumors. In: Rankow RM, Polayes IM, editors. Disease of the Salivary Glands. Philadelphia, Pa: WB Saunders Co.; 1976. p. 99-142.
4. Purohit J, Desai VD, Sharma R, Sharma AK. Mucoepidermoid carcinoma of paroƟ d gland: A case report. Saudi J Oral Sci 2015;2:106-9.
5. Ananthaneni A, Ponnapalli H, Kiresur MA, Chaitanya SK. Mucoepidermoid carcinoma involving the palate with lamellated calcifications: A notable finding. Eur J Gen Dent. 2016; 1, 5(1):35-8.
6. Gonçalo R, Dantas A, Morais E, Freitas R. Mucoepidermoid carcinoma of the retromolar region: case report. J Bras Patol Med Lab. 2020; 56: 1-4.
7. Barnes L, Eveson JW, Sidransky D, Reichart P. World Health Organization classification of tumors: pathology and genetics of head and neck tumors. IARC Press: Lyon; 2005.
8. Janet-Ofelia GC, Rafael MV, Guillermo GA, et al. Mucoepidermoid carcinoma of the salivary glands: survival and prognostic factors. J Maxillofac Oral Surg. 2017;16(4): 431-437. PubMed PMID: 29038625.
9. Spiro RH. Salivary neoplasms: Overview of a 35-year experience with 2,807 patients. Head Neck Surg 1986;8:177-84.
10. Ostman J, Anneroth G, Gustafsson H, Tavelin B. Malignant salivary gland tumours in Sweden 1960-1989 — An epidemiological study. Oral Oncol 1997;33:169-76.
11. Dillard DG, Muller S, Cohen C, Bloch D, Del Gaudio JM, Gal AA. High tumor grade in salivary gland mucoepidermoid carcinomas and loss of expression of transforming growth factor beta receptor type II. Arch Otolaryngol Head Neck Surg 2001;127:683-6.
12. Auclair PL, Goode RK, Ellis GL. Mucoepidermoid carcinoma of intraoral salivary glands. Evaluation on and application on of grading criteria in 143 cases. Cancer 1992;69:2021-30.
13. Kullaje S, Prabhu V, Thomas S, Keshava PY. Mucoepidermoid carcinoma of the anterior maxilla: A rare entity. Arch Med Health Sci 2014;2:64-6.
14. F. R. Pires, O. P. Almeida, M. A. Lopes, D. E. C. Perez, and L. P. Kowalski, “Central mucoepidermoid carcinoma of the mandible: report of four cases with long-term follow-up,” International Journal of Oral and Maxillofacial Surgery, vol. 32, no. 4, pp. 378–382, 2003.
15. Raut DL, Khedkar SA. Primary intraosseous mucoepidermoid carcinoma of the maxilla: A case report and review of literature. Dentomaxillofac Radiol 2009;38:163-8.
16. Brookstone MS, Huvos AG. Central salivary tumors of the maxilla and mandible: a clinicapathologic study of 11 cases with an analysis of the literature. J Oral Maxillofac Surg 1992; 50:229–236.
17. Dhawan IK, Bhargava S, Nayak NC, Gupta RK. Central salivary gland tumors of jaws. Cancer 1970; 26: 211–217.
18. DL Raut, SA Khedkar. Primary intraosseous mucoepidermoid carcinoma of the maxilla: a case report and review of literature. Dentomaxillofacial Radiology (2009) 38, 163–168.
19. Alos L, Lujan B, CasƟ llo M, Nadal A, Carreras M, Caballero M, et al. Expression of membrane-bound mucins (MUC1 and MUC4) and secreted mucins (MUC2, MUC5AC, MUC5B, MUC6 and MUC7) in mucoepidermoid carcinomas of salivary glands. Am J Surg Pathol 2005;29:806-13.
20. Handra-Luca A, Lamas G, Bertrand JC, Fouret P. MUC1, MUC2, MUC4, and MUC5AC expression in salivary gland mucoepidermoid carcinoma: Diagnostic and prognostic implications. Am J Surg Pathol 2005;29:881-9.
21. Yoon JH, Ahn SG, Kim SG, Kim J. Calcifications in a clear cell mucoepidermoid carcinoma of the hard palate. Int. J Oral Maxillofac. Surg. 2005; 34(8):927-9.
Published
2024-12-19
How to Cite
Arpan Manna. (2024). Unusual Presentation of a Huge Mucoepidermoid Carcinoma – A Case Report. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 10(4). https://doi.org/10.21276/ujds.2024.10.4.11
Section
Case Reports
