Estimation Of Adherance Of Candida Albicans To Different Denture Base Materials And Its Relationship With Denture Stomatitis – An In Vivo Study

  • Varun Saini Assistant Professor
  • neha saini Reader, NIMS Dental College & Hospital , Jaipur
  • Dr Vaibhav Avnish MD (Anaesthesiology ) Associate Professor & HOD, RUHS College of Medical Sciences ,Jaipur, India
  • Rohit Mundra
  • Varun kumar Saini
  • Dr Saurabh Jain MDS (Periodontics ), Medical Officer (Dental)Community Health Centre,Nawacity,Nagaur, Rajasthan
Keywords: Candida albicans , edentulous, dentures , DPI , Lucitone 199 heat cure acrylics


Background - Candida albicans  is the most common human oral fungi frequently recovered from the denture surface causing denture stomatitis. Modern treatment approaches suppress the normal host defense mechanisms, alter the normal human microbial flora& allow non bacterial species to become more prevalent in commensal flora.

Aims & Objectives - The objective of the present study was to evaluate the prevalence & incidence of Candida albicans in DPI & Lucitone 199 heat cure acrylic denture wearers & its relationship with denture stomatitis.

Materials & Methods – The study was conducted at our institution wherein  52 edentulous patients enrolled in the study .These patients were randomly assigned to two groups DPI and Lucitone 199 . Dentures were made using the two materials . At three months follow up swab samples were taken from the denture surfaces and sent to lab for culture .

Result – The prevalence of Candida albicans in denture wearers was found to be 23%. The incidence of denture stomatitis was 27%. Prevalence of Candida albicans &  incidence of denture stomatitis was less with Lucitone 199 heat cure acrylic dentures.

Conclusion - Any treatment that we do should not be cause of other pathology. Denture stomatitis falls into such category.  Follow up should be done on a mandatory basis to evaluate the changes & performing necessary modifications.


1. D R Radford , S J Challacombe, J D Walter. Denture plaque and adherence of Candida albicans to denture-base materials in vivo and in vitro .Crit Rev Oral Biol Med . 1999;10(1):99-116.
2. Elham Emami , Jacynthe Séguin, Pierre H Rompré, Louis de Koninck, Pierre de Grandmont, Jean Barbeau . The relationship of myceliated colonies of Candida albicans with denture stomatitis: an in vivo/in vitro study . Int J Prosthodont. . 2007;20(5):514-20.
3. Charles L. Bolender , George A. Zarb , Rhonda Jacob , Steven Eckert. Bouchers Prosthodontics treatment of edentulous patients. Mosby . 11 th edition
4. E Budtz-Jörgensen . The significance of Candida albicans in denture stomatitis. Scand J Dent Res . 1974;82(2):151-90.
5. Robert B. Peters, Arthur N. Bahn, Gaida Barens .Candida albicans in the Oral Cavities of Diabetics .J Dent Res 1966;45 (3): 771
6. Ananthanarayan and Paniker's Textbook of Microbiology .Orient Blackswan, .10th edition
7. Tatiana Pereira-Cenci , Altair Antoninha Del Bel Cury, Wim Crielaard, Jacob Martien. Ten Cate Development of Candida-associated denture stomatitis: new insights . J Appl Oral Sci. 2008;16(2):86-94.
8. S R Lockhart , S Joly, K Vargas, J Swails-Wenger, L Enger, D R Soll. Natural defenses against Candida colonization breakdown in the oral cavities of the elderly.J Dent Res .1999 ;78(4):857-68.
9. F. R. Pires , E. B. D. Santos ,P. R. F. Bonan ,O. P. De Almeida ,M. A. Lopes. Denture stomatitis and salivary Candida in Brazilian edentulous patients .J Oral Rehab . 2002 ;29(11):1115-1119.
10. . Rajni kalla , Harikesh rao,Sunil kumar MV. Surface adherence of Candida albicans to different poly methyl metha acrylate denture base resins: An invitro study. International journal of prosthetic dentistry 2011;2(1):2-7
11. L.P.Samaranayake ,J.McCourtie ,T.W.MacFarlane . Factors affecting the in-vitro adherence of Candida albicans to acrylic surfaces. Archives of Oral Biology.1980; 25(8–9): 611-615.
12. E Budtz-Jorgensen, U Bertram Denture stomatitis. I. The etiology in relation to trauma and infection. Acta Odontol Scand .1970 Mar;28(1):71-92
13. . Dhir G, Berzins DW, Dhuru VB, Periathamby AR, Dentino A. Physical properties of denture base resins potentially resistant to Candida adhesion. J Prosthodont. 2007;16(6):465-472. doi:10.1111/j.1532-849X.2007.00219.x
14. . Sang E. Park DDS, ,Antony Raj Periathamby ,Juan C. Loza . Effect of surface‐charged poly(methyl methacrylate) on the adhesion of Candida albicans . Journal of prosthodontics .2003;12(4): 249-254.
How to Cite
Varun Saini, neha saini, Dr Vaibhav Avnish, Rohit Mundra, Varun kumar Saini, & Dr Saurabh Jain. (2021). Estimation Of Adherance Of Candida Albicans To Different Denture Base Materials And Its Relationship With Denture Stomatitis – An In Vivo Study. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 7(3).