Tooth Tattoo: A New Paradigm to Detect Bacteria on Teeth Enamel
Keywords:
Tooth tattoo, graphene, nano sensor
Abstract
Oral health is an integral part of good overall health. Dental caries and periodontitis are the most common chronic infectious oral diseases. With a greater understanding of dental caries and periodontal diseases comes an opportunity to promote ‘preventive & interceptive therapy’ much before the onset and progression of the disease. Central to this is early diagnosis. But many yester year diagnostic tools lack selectivity and sensitivity and others being expensive, limit the opportunity for early diagnosis. Researchers at Princeton University, New Jersey led by Micheal McAlpine and Tufts bioengineers Fiorenzo Omenetto, David Kaplan and Hu Tao have developed a tiny graphene nanosensor device for early and highly sensitive detection of bacteria on human enamel and assess patient’s oral health, which they have called Tooth tattoo. The team first published their research in the journal, Nature Communications. Presently the prototype being studied, represents versatile approach just not for caries and periodontal disease detection but could provide window to patient’s overall health.
References
1. G. H. Petersson and D. Bratthall, “The caries decline: a review of reviews,” European Journal of Oral Sciences 1996; 104(4):436–443.
2. G. D. Slade and A. J. Spencer, “Distribution of coronal and root caries experience among persons aged 60+ in South Australia”. Australian Dental Journal 1997; 42(3): 178–184.
3. Petersen PE: The World Oral Health Report. Geneva, Switzerland: World Health Organization; 2003.
4. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C: The global burden of oral disease and risks to oral health. Bull World Health Organ 2005; 83(9):661-9.
5. Beltran-Aguilar ED, Barker LK, Canto MT, Dye BA, Gooch BF, Griffin SO, et al.: Surveillance for dental caries, dental sealants, tooth retention, edentulism, and enamel fluorosis – United States, 1988–1994 and 1999–2002. In MMWR CDC Surveill. Volume 54. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2005:1-44.
6. P.I. Eke, B.A. Dye, L. Wei, G.O. Thornton-Evans, and R.J. Genco. Prevalence of Periodontitis in Adults in the United States: 2009 and 2010. J DENT RES 2012; 91(10):914-20.
7. Al-Khateeb S, Oliveby A, de Josselin de Jong E, Angmar-Mansson B. Laser fluorescence quantification of remineralisation in situ of incipient enamel lesions: influence of fluoride supplements. Caries Research 1997; 31(2):132–40.
8. Amaechi BT, Higham SM. In vitro remineralisation of erodedenamel lesions by saliva.
Journal of Dentistry 2001; 29(5):371–6.
9. Pitts NB. Clinical diagnosis of dental caries: a European perspective. Journal of Dental Education 2001; 65(10):972–8.
10. Larry A. Sweeting, Karen Davis, Charles M. Cobb. Periodontal Treatment Protocol (PTP) for the General Dental Practice. American Dental Hygienists' Association. July 2012.
11. Antonio Castro Neto, Francisco Guinea and Nuno Miguel Peres.Drawing conclusions from graphene. Physics World November 2006.
12. William Putzbach 1,2 and Niina J. Ronkainen. Immobilization Techniques in the Fabrication of Nanomaterial-Based Electrochemical Biosensors: A Review Sensors 2013; 13(4): 4811-4840.
13. Hummers WS, Offeman RE. Preparation of Graphitic Oxide. J Am Chem Soc 1958; 80:1339-1339.
14. Naldini L, Blömer U, Gallay P. et al. In Vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272(5259):263-7.
15. Markovic ZM, Harhaji-Trajkovic LM, Todorovic-Markovic BM. et al. In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes. Biomaterials 2011; 32:1121-1129.
16. Ran Li, Yanhong Tan and Hongwei Wang.Detection of Promyelocytic Leukemia/Retinoic Acid Receptor α (PML/RARα) Fusion Gene with Functionalized Graphene Oxide. Int J Mol Sci 2013; 14(6):12863-12872.
17. Loh KP, Bao QL, Eda G. et al. Graphene oxide as a chemically tunable platform for optical applications. Nat chem. 2010; 2:1015–1024.
18. Akhavan O, Ghaderi E. Toxicity of graphene and graphene oxide nanowalls against bacteria. ACS Nano. 2010; 4(10):5731-5736
19. Ryoo SR, Kim YK, Kim MH. et al. Behaviors of NIH-3T3 fibroblasts on graphene/carbon nanotubes: Proliferation, focal adhesion, and gene transfection studies. ACS Nano. 2010; 4(11):6587-6598
20. S.Prasong, S.Wilaiwan and K.Nualchai. Structure thermal characteristics of Bombyx mori silk fibroin films: Effect of different organic solvents. International Journal of Chemical Technologies 2010; 2(1):21-27.
21. Xiaohua Huang,Prashant K Jain,Ivan H El-Sayed &Mostafa A El-SayedGold nanoparticles: interesting opticalproperties and recent applications in cancerdiagnostics and therapy. Nanomedicine 2007; 2(5): 681–693.
22. Manu S. Mannoor, Hu Tao, Jefferson D. Clayton, Amartya Sengupta, David L. Kaplan, Rajesh R. Naik, Naveen Verma, Fiorenzo G. Omenetto2 & Michael C. McAlpine. Graphene - based wireless bacteria detection on tooth enamel. Nature Communication 2012; 3(763):1-8.
23. Kharat N, Singhai A, Prasant M.C, Patil A.K, Ali F.M – A TOOTH TATTOO WITH A PURPOSE: AN INNOVATIVE APPROACH. J Evol Med Dent Sci 2014; 3(04):921-925
2. G. D. Slade and A. J. Spencer, “Distribution of coronal and root caries experience among persons aged 60+ in South Australia”. Australian Dental Journal 1997; 42(3): 178–184.
3. Petersen PE: The World Oral Health Report. Geneva, Switzerland: World Health Organization; 2003.
4. Petersen PE, Bourgeois D, Ogawa H, Estupinan-Day S, Ndiaye C: The global burden of oral disease and risks to oral health. Bull World Health Organ 2005; 83(9):661-9.
5. Beltran-Aguilar ED, Barker LK, Canto MT, Dye BA, Gooch BF, Griffin SO, et al.: Surveillance for dental caries, dental sealants, tooth retention, edentulism, and enamel fluorosis – United States, 1988–1994 and 1999–2002. In MMWR CDC Surveill. Volume 54. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention; 2005:1-44.
6. P.I. Eke, B.A. Dye, L. Wei, G.O. Thornton-Evans, and R.J. Genco. Prevalence of Periodontitis in Adults in the United States: 2009 and 2010. J DENT RES 2012; 91(10):914-20.
7. Al-Khateeb S, Oliveby A, de Josselin de Jong E, Angmar-Mansson B. Laser fluorescence quantification of remineralisation in situ of incipient enamel lesions: influence of fluoride supplements. Caries Research 1997; 31(2):132–40.
8. Amaechi BT, Higham SM. In vitro remineralisation of erodedenamel lesions by saliva.
Journal of Dentistry 2001; 29(5):371–6.
9. Pitts NB. Clinical diagnosis of dental caries: a European perspective. Journal of Dental Education 2001; 65(10):972–8.
10. Larry A. Sweeting, Karen Davis, Charles M. Cobb. Periodontal Treatment Protocol (PTP) for the General Dental Practice. American Dental Hygienists' Association. July 2012.
11. Antonio Castro Neto, Francisco Guinea and Nuno Miguel Peres.Drawing conclusions from graphene. Physics World November 2006.
12. William Putzbach 1,2 and Niina J. Ronkainen. Immobilization Techniques in the Fabrication of Nanomaterial-Based Electrochemical Biosensors: A Review Sensors 2013; 13(4): 4811-4840.
13. Hummers WS, Offeman RE. Preparation of Graphitic Oxide. J Am Chem Soc 1958; 80:1339-1339.
14. Naldini L, Blömer U, Gallay P. et al. In Vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector. Science 1996; 272(5259):263-7.
15. Markovic ZM, Harhaji-Trajkovic LM, Todorovic-Markovic BM. et al. In vitro comparison of the photothermal anticancer activity of graphene nanoparticles and carbon nanotubes. Biomaterials 2011; 32:1121-1129.
16. Ran Li, Yanhong Tan and Hongwei Wang.Detection of Promyelocytic Leukemia/Retinoic Acid Receptor α (PML/RARα) Fusion Gene with Functionalized Graphene Oxide. Int J Mol Sci 2013; 14(6):12863-12872.
17. Loh KP, Bao QL, Eda G. et al. Graphene oxide as a chemically tunable platform for optical applications. Nat chem. 2010; 2:1015–1024.
18. Akhavan O, Ghaderi E. Toxicity of graphene and graphene oxide nanowalls against bacteria. ACS Nano. 2010; 4(10):5731-5736
19. Ryoo SR, Kim YK, Kim MH. et al. Behaviors of NIH-3T3 fibroblasts on graphene/carbon nanotubes: Proliferation, focal adhesion, and gene transfection studies. ACS Nano. 2010; 4(11):6587-6598
20. S.Prasong, S.Wilaiwan and K.Nualchai. Structure thermal characteristics of Bombyx mori silk fibroin films: Effect of different organic solvents. International Journal of Chemical Technologies 2010; 2(1):21-27.
21. Xiaohua Huang,Prashant K Jain,Ivan H El-Sayed &Mostafa A El-SayedGold nanoparticles: interesting opticalproperties and recent applications in cancerdiagnostics and therapy. Nanomedicine 2007; 2(5): 681–693.
22. Manu S. Mannoor, Hu Tao, Jefferson D. Clayton, Amartya Sengupta, David L. Kaplan, Rajesh R. Naik, Naveen Verma, Fiorenzo G. Omenetto2 & Michael C. McAlpine. Graphene - based wireless bacteria detection on tooth enamel. Nature Communication 2012; 3(763):1-8.
23. Kharat N, Singhai A, Prasant M.C, Patil A.K, Ali F.M – A TOOTH TATTOO WITH A PURPOSE: AN INNOVATIVE APPROACH. J Evol Med Dent Sci 2014; 3(04):921-925
Published
2021-06-03
How to Cite
Borkar, K. (2021). Tooth Tattoo: A New Paradigm to Detect Bacteria on Teeth Enamel. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 7(2). https://doi.org/10.21276//ujds.2021.7.2.30
Section
Review Article
