COMPARATIVE EVALUATION OF HYDROXYAPATITE AND BIOACTIVE GLASS IN THE TREATMENT OF 3-WALL INTRABONY DEFECTS IN CHRONIC PERIODONTITIS: A RANDOMIZED CONTROLLED CLINICAL TRIAL

Abstract

Aim: The present study aims to explore the clinical and radiographic efficacy of two alloplastic materials, hydroxy apatite and bioactive glass in the treatment of 3-wall intrabony defects in patients with chronic periodontitis.
Methods: Eighty four 3-wall intrabony defects were randomly allocated for treatment with either Hydroxyapatitite (HA) with open-flap debridement or Bioactive glass (BG) with open-flap debridement or open-flap debridement (OFD) alone. Clinical and radiologic parameters, such as probing depth (PD), clinical attachment level (CAL), intrabony defect depth, and percentage defect fill, was recorded at baseline and 6 months postoperatively

Results: Mean PD reduction and CAL gain were greater in BG (3.07+0.62and 2.63+0.63 mm) and HA (3.48+0.51mm and2.48+0.64mm) groups than the control (OFD alone) group(2.74+0.62 and 2.0+0.65 mm) respectively. Furthermore, a significantly greater percentage of mean defect fill was found in the BG (48.71+4.55 %) and HA (46.38+5.17) groups compared with the control (27.04+4.58 %) group(P<0.001). Conclusion: Within the limitations of the present study, there was similar PD reduction, CAL gain, and defect fill at sites treated with Hydroxyapatite or Bioactive glass. However, there was significant improvement in the clinical parameters in the grafted sites when compared to OFD alone.