ASSESSMENT OF SALIVARY LEVEL OF LEPTIN IN OBESE PATIENTS WITH CHRONIC PERIODONTITIS

Amrita; Singh Akanksha; Kumari Anupama; Kumari Nidhi; Kumar Amit; Kumar Vivek

Amrita Department of Periodontology and Oral Implantology, Uttaranchal Dental and Medical Research Institute, Dehradun
Singh Akanksha Department of Periodontology and Oral Implantology, Maharana Pratap Dental College, Kanpur
Kumari Anupama Department of Oral and Maxillofacial Surgery, Hazaribag College of Dental Sciences and Hospital, Hazaribagh
Kumari Nidhi Oral and Maxillofacial Surgery, Buddha Institute of Dental Sciences and Hospital, Patna
Kumar Amit Oral and Maxillofacial Surgery, Buddha Institute of Dental Sciences and Hospital, Patna
Kumar Vivek Department of Periodontology and Oral Implantology, Hazaribag College of Dental Sciences and Hospital, Hazaribagh

Keywords: Saliva, obesity, periodontitis, leptin

Abstract

Aims and objectives: The current study was designed with an aim to assess the level of salivary leptin in obese patients with and without chronic periodontitis and non-obese healthy patients.
Materials and Methods: A total of 45 patients were divided into 3 groups. Group 1: Non-obese healthy, Group 2: obese without chronic periodontitis and Group3: obese with chronic periodontitis. Whole saliva samples were collected, and leptin levels were evaluated by standard enzyme-linked immunosorbent assay. The results were analyzed by SPSS and Mann–Whitney analysis.
Results: The highest leptin levels from the Saliva were detected in group 2 while the lowest were detected in group 3. A significant difference in leptin levels in the saliva was found in all the groups.

Conclusion: The level of leptin was lower in the saliva of chronic periodontitis patients. Leptin may be used as an inflammatory marker for the detection of periodontal disease.