ASSESSMENT OF SALIVARY LEVEL OF LEPTIN IN OBESE PATIENTS WITH CHRONIC PERIODONTITIS
Abstract
Aims and objectives: The current study was designed with an aim to assess the level of salivary leptin in obese patients with and without chronic periodontitis and non-obese healthy patients.
Materials and Methods: A total of 45 patients were divided into 3 groups. Group 1: Non-obese healthy, Group 2: obese without chronic periodontitis and Group3: obese with chronic periodontitis. Whole saliva samples were collected, and leptin levels were evaluated by standard enzyme-linked immunosorbent assay. The results were analyzed by SPSS and Mann–Whitney analysis.
Results: The highest leptin levels from the Saliva were detected in group 2 while the lowest were detected in group 3. A significant difference in leptin levels in the saliva was found in all the groups.
Conclusion: The level of leptin was lower in the saliva of chronic periodontitis patients. Leptin may be used as an inflammatory marker for the detection of periodontal disease.