ASSESSMENT OF SALIVARY LEVEL OF LEPTIN IN OBESE PATIENTS WITH CHRONIC PERIODONTITIS

  • Amrita Department of Periodontology and Oral Implantology, Uttaranchal Dental and Medical Research Institute, Dehradun
  • Singh Akanksha Department of Periodontology and Oral Implantology, Maharana Pratap Dental College, Kanpur
  • Kumari Anupama Department of Oral and Maxillofacial Surgery, Hazaribag College of Dental Sciences and Hospital, Hazaribagh
  • Kumari Nidhi Oral and Maxillofacial Surgery, Buddha Institute of Dental Sciences and Hospital, Patna
  • Kumar Amit Oral and Maxillofacial Surgery, Buddha Institute of Dental Sciences and Hospital, Patna
  • Kumar Vivek Department of Periodontology and Oral Implantology, Hazaribag College of Dental Sciences and Hospital, Hazaribagh
Keywords: Saliva, obesity, periodontitis, leptin

Abstract

Aims and objectives: The current study was designed with an aim to assess the level of salivary leptin in obese patients with and without chronic periodontitis and non-obese healthy patients.
Materials and Methods: A total of 45 patients were divided into 3 groups. Group 1: Non-obese healthy, Group 2: obese without chronic periodontitis and Group3: obese with chronic periodontitis. Whole saliva samples were collected, and leptin levels were evaluated by standard enzyme-linked immunosorbent assay. The results were analyzed by SPSS and Mann–Whitney analysis.
Results: The highest leptin levels from the Saliva were detected in group 2 while the lowest were detected in group 3. A significant difference in leptin levels in the saliva was found in all the groups.

Conclusion: The level of leptin was lower in the saliva of chronic periodontitis patients. Leptin may be used as an inflammatory marker for the detection of periodontal disease.

Published
2020-02-04
How to Cite
Amrita, Singh Akanksha, Kumari Anupama, Kumari Nidhi, Kumar Amit, & Kumar Vivek. (2020). ASSESSMENT OF SALIVARY LEVEL OF LEPTIN IN OBESE PATIENTS WITH CHRONIC PERIODONTITIS. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 5(3), 01-05. Retrieved from https://ujds.in/index.php/ujds/article/view/116