Cemento-Ossifying Fibroma: A Comprehensive Exploration Through a Striking Case Report
Cemento-Ossifying Fibroma
Keywords:
Cemento-Ossifying Fibroma, COsF, mandible, swelling, Orthopantomograph, OPG
Abstract
Cemento-ossifying fibroma (COsF) is a benign mesenchymal odontogenic tumor. The origin of COsF occurs within the periodontal ligament, housing multipotent stem cells capable of generating cementum, lamellar bone, and/or fibrous tissue. This case report of a 35-year-old male reported swelling in the left lower posterior jaw region over the past year. The objective of this report is to provide clinicians and researchers with insights into the diagnostic challenges, treatment modalities, and the evolving landscape of COF, facilitating improved patient management and furthering the discourse on this intriguing maxillofacial pathology.
References
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2. Ram R, Singhal A, Singhal P. Cemento-ossifying fibroma. Contemp Clin Dent. 2012 Jan;3(1):83-5. doi: 10.4103/0976-237X.94553. PMID: 22557904; PMCID: PMC3341766.
3. Bala TK, Soni S, Dayal P, Ghosh I. Cemento-ossifying fibroma of the mandible. A clinicopathological report. Saudi Med J. 2017 May;38(5):541-545. doi: 10.15537/smj.2017.5.15643. PMID: 28439606; PMCID: PMC5447217.
4. Kaur T, Dhawan A, Bhullar RS, Gupta S. Cemento-Ossifying Fibroma in Maxillofacial Region: A Series of 16 Cases. J Maxillofac Oral Surg. 2021 Jun;20(2):240-245. doi: 10.1007/s12663-019-01304-y. Epub 2019 Nov 8. PMID: 33927492; PMCID: PMC8041960.
5. Trijolet J, Parmentier J, Sury F, Goga D, Mejean N, Laure B. Cemento-ossifying fibroma of the mandible. European Annals of Otorhinolaryngology, Head and Neck Diseases. 2011 Jan;128(1):30-3.
6. Langlais RP, Langland OE, Nortje CI. Diagnostic imaging of the jaws. Baltimore: Williams and Wilkins; 1995. p. 555.
7. Mithra R, Baskaran P, Sathyakumar M. Imaging in the diagnosis of cemento-ossifying fibroma: a case series. J Clin Imaging Sci. 2012;2:52. doi: 10.4103/2156-7514.100373. Epub 2012 Aug 30. PMID: 23029635; PMCID: PMC3440937.
8. El-Naggar AK, John KC, Grandis JR, Takata T, Slootweg PJ. WHO Classification of Head and Neck Tumours. 4th ed. Lyon: IARC; 2017
9. de Mesquita Netto AC, Gomez RS, Diniz MG, Fonseca-Silva T, Campos K, De Marco L, Carlos R, Gomes CC. Assessing the contribution of HRPT2 to the pathogenesis of jaw fibrous dysplasia, ossifying fibroma, and osteosarcoma. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;115:359–67.
10. Coura BP, Bernardes VF, de Sousa SF, Diniz MG, Moreira RG, de Andrade BAB, Romañach MJ, Pontes HAR, Gomez RS, Odell EW, Gomes CC. Targeted next-generation sequencing and allele-specific quantitative pcr of laser capture microdissected samples uncover molecular differences in mixed odontogenic tumors. J Mol Diagn. 2020;22:1393–99.
11. Vura NG, Gaddipati R, Ramisetti S, Kumara R, Reddy R, Kanchi U. Surgical Management of Ossifying Fibroma in Maxilla: Report of Two Cases. J Int Oral Health. 2015 Jun;7(6):115-8. PMID: 26124613; PMCID: PMC4479764.
12. Waldron CA, Giansanti JS. Benign fibro-osseous lesions of the jaws: a clinical-radiologic-histologic review of sixty-five cases. II. Benign fibro-osseous lesions of periodontal ligament origin. Oral Surg Oral Med Oral Pathol. 1973 Mar;35(3):340-50. doi: 10.1016/0030-4220(73)90072-8. PMID: 4510606.
13. Barberi A, Cappabianca S, Collela G. Bilateral cement-ossifying fibroma of the maxillary sinus. Br J Radiol 2003;76:279-80
14. White SC, Pharoah MJ. Oral Radiology 6th ed. China: Mosby Co; 2009.p.440-1.
Published
2024-10-23
How to Cite
MANDLIK, D. R. (2024). Cemento-Ossifying Fibroma: A Comprehensive Exploration Through a Striking Case Report. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 10(4). https://doi.org/10.21276/ujds.2024.10.4.8
Section
Case Reports
