Bioactive Material in Pediatric Dentistry

  • DR AKHAND PRATAP SINGH Singh Sardar Patel post graduate Institute of dental and medical sciences Lucknow
Keywords: Bioactivity, Bioresponsive Biomimetic, Biocompatibility, Biomineralization, Repair/ regeneration, Nanocomposite.

Abstract

A new generation of bioactive materials which has been developed during the last ten years has been used in every field of dentistry and medicine. These bioactive materials are able to release calcium, phosphate and other specific ions to help rebuild demineralized dentin and enamel. These materials are broadly used in the field of conservative dentistry for regeneration, repair and reconstruction. These materials are available in different form and composition that acts directly on vital tissue inducing its healing and repair. These materials directly function because of induction of various growth factors and different cells. New innovations are necessary to continue to help reinforce existing technologies and to introduce new paradigms for treating dental disease and restoring teeth seriously compromised by caries lesions via biomimetic and more biological operative approaches. Bioactive materials with nanoscale structure, including nanomedicine, nanodevices, nanomaterials, such as nanofibres and nanocomposites, can be designed and produced from natural biopolymers, synthetic polymers and inorganic substances. The nanocomposite-based scaffold allows for cell growth, yielding a unique composite system.

References

1. Asthana G, Bhargava S. Bioactive material: A Comprehensive Review. Sch. J. App. Med. Sci., 2014; 2(6): 3231-3237.
2. Sonarkar S, Purba R, “Bioactive materials in conservative dentistry. International Journal of Contemporary Dental and Medical Reviews, Vol.2015.
3. Vallittu PK, Boccaccini AR, Hupa L, Watts DC. Bioactive dental materials -Do they exist and what does bioactivity mean. Dent Mater 2018 May; 34(5): 693 - 694.
4. L. L. Hench, "Bioactive Glasses and Glass-Ceramics", Materials Science Forum 1999; 293(3), 37 - 64.
5. Foreman PC and Barnes IE. A review of calcium hydroxide. International Endodontic Journal 1990; 23: 283 - 297.
6. Baranwal R, Singh BD, Dubey A, Avinash A. Calcium Hydroxide in Dentistry. Chettinad Health City Medical Journal 2016; 5(1): 30 - 33.
7. Camilleri J and Pitt Ford TR. Mineral trioxide aggregate: a review of the constituents and biological properties of the material. International Endodontic Journal 2016; 39(2): 747 - 754.
8. Macwan C, Deshpande A. Mineral trioxide aggregate (MTA) in dentistry: A review of literature. J Oral Res Rev 2014; 6(1): 71 - 74.
9. Kabbinale P, Chethena KC, Kuttappa MA. Role of calcium-enriched mixture in endodontics. Archives of Medicine and Health Sciences /Jan-Jun 2015; 35(1): 58 - 62.
10. Singh H, Kaur M, Markan S, Kapoor P. Biodentine: A Promising Dentin substitute. J Interdiscipl Med Dent Sci 2014, 2(1): 5-11.
11. Niinuma A. Newly developed resinous direct pulp capping agent containing calcium hydroxide (MTYA1-Ca). International Endodontic Journal 1999; 32: 475 - 483.
12. Chatzistavrou X et al. Development of new sol-gel derived Ag-doped biomaterials for dental applications. Materials Research Society 2012; 1417: 39 – 46.
13. Al-Sanabani JS, Madfa AA, Al-Sanabani FA. Application of Calcium Phosphate Materials in Dentistry. International Journal of Biomaterials 2013; 32(5): 312 - 324.
14. Zhong Y et.al. Effect of a novel bioactive glass-ceramic on dentinal tubule occlusion: an in vitro study. Australian Dental Journal 2015; 60: 96 - 103.
15. Pathak SD et al. Advances in Pulp Capping Materials: A Review. IOSR Journal of Dental and Medical Sciences 2017; 16(2): 31 - 37.
16. Dowling A.P. Development of nanotechnologies. Nano Today, 2004, December,30
17. Taniguchi N. On the basic concept of ‘nano-technology’. Proceedings of the International Conference on Production, London, Part II, 1974. British Society of Precision Engineering.
18. http://www.marketwire.com/mw/emailprcntct?id=F758DE38FCF1CCB2 440-684-9600, Source: Freedonia Group, Inc.
19. Kay S., Thapa A., Haberstroh K.M., and Webster T.J. Nanostructured polymer nanophase ceramic composites enhance osteoblast and chondrocyte adhesion.Tissue Engng, 2002, 8, 753–761.
20. Frost and Sullivan. World Polymer Nanocomposites Markets, 2007.
21. Poole-Warren L.A., Farrugia B., Fong N., Hume E., and Simmons A. Controlling cell–material interactions with polymer nanocomposites by use of surface modifying additives. Appl. Surf. Sci., 2008, 255, 519–522.
22. Zhao X. Bioactive materials and nanotechnology. Woodhead Publishing Limited 2011; 35(6): 50 - 69.
Published
2021-05-28
How to Cite
Singh, D. A. P. S. (2021). Bioactive Material in Pediatric Dentistry. UNIVERSITY JOURNAL OF DENTAL SCIENCES, 7(2). https://doi.org/10.21276//ujds.2021.7.2.24